Cerebellar ataxias: β-III spectrin's interactions suggest common pathogenic pathways
نویسندگان
چکیده
منابع مشابه
Cerebellar ataxias: β‐III spectrin's interactions suggest common pathogenic pathways
Spinocerebellar ataxias (SCAs) are a genetically heterogeneous group of disorders all characterised by postural abnormalities, motor deficits and cerebellar degeneration. Animal and in vitro models have revealed β-III spectrin, a cytoskeletal protein present throughout the soma and dendritic tree of cerebellar Purkinje cells, to be required for the maintenance of dendritic architecture and for ...
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ژورنال
عنوان ژورنال: The Journal of Physiology
سال: 2016
ISSN: 0022-3751
DOI: 10.1113/jp271195